The course encompasses topics such as Introduction to Medical Biology, Origin of life, Tools of Cell Biologist, Cellular Organisation of Life, Cell membrane, Cytoskeleton, Cell adhesion, Cell signaling events, Intercellular cell signaling, Programmed cell death, Cell cycle, Principles of Laboratory, DNA extraction, Organic chemical reaction basis of the human body, Introduction to Biophysics; Physical Measurements and Units, Unit standards, Force, Gravity, Gravitation Law, Mass and Weight; Newton’s Laws, Center of Mass, Gravitation, Energy, Kinetic and Potential Energy, Energy Protection Principle; Velocity, Acceleration, Moment; Problem Solution Practices, Biomaterials: Elastomers, Hook’s Law, Young’s Modulus, Bioelectronics: Bioelectrical Activity, Electric Current Effects; Bioelectronics: Membrane Impedance, Electrical Security Systems
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Course Learning Outcomes
| Language of Instruction | English |
| Course Level | Undergraduate |
| Course Type | Compulsory |
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Course Coordinator
Vice Coordinator |
Prof.Dr. İnci Özden
Assist.Prof.Dr. Müge Kopuz Alvarez Noval |
| Instructors |
Prof.Dr.Turgay İsbir,PhD
Assoc.Prof.Dr. Soner Doğan,PhD Assoc.Prof.Dr. Deniz Kıraç,PhD Assoc.Prof.Dr. Seda Güleç Yılmaz Assist.Prof.Dr.Akif Meherem,PhD Assoc.Prof.Dr. Bilge Güvenç Tuna, PhD Assoc.Prof.Dr. Esra Önen Bayram,PhD Assoc.Prof.Dr. Aylin Yaba Uçar,PhD Assist.Prof.Dr.Alev Cumbul ,PhD
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| Assistants | - |
| Goals | This course is conducted with the collaboration of the departments of Medical Biology, Biophysics, Medical Organic Chemistry and Histology and Embryology. The course aims to make a general introduction to the biomedical sciences. |
| Content |
The course encompasses topics such as Introduction to Medical Biology, Origin of life, Tools of Cell Biologist, Cellular Organisation of Life, Cell membrane, Cytoskeleton, Cell adhesion, Cell signaling events, Intercellular cell signaling, Programmed cell death, Cell cycle, Principles of Laboratory, DNA extraction, Organic chemical reaction basis of the human body, Introduction to Biophysics; Physical Measurements and Units, Unit standards, Force, Gravity, Gravitation Law, Mass and Weight; Newton’s Laws, Center of Mass, Gravitation, Energy, Kinetic and Potential Energy, Energy Protection Principle; Velocity, Acceleration, Moment; Problem Solution Practices, Biomaterials: Elastomers, Hook’s Law, Young’s Modulus, Bioelectronics: Bioelectrical Activity, Electric Current Effects; Bioelectronics: Membrane Impedance, Electrical Security Systems
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| Learning Outcomes | Programme learning outcomes | Teaching Methods | Assessment Methods |
| Define the molecular perspective to all of the biochemical mechanisms in living cells, | PLO 9,15 | 1, 2, 3, 4, | A, B |
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Explain human genome project and the importance of the results of this project for the future of biology and health sciences.
|
PLO 9,15 | 1, 2, 3, 4, | A, B |
| Identify the theory of evolution and define the stages of evolution to the formation of the human genome. | PLO 9,15 | 1, 2, 3, 4, | A, B |
| Explain the methods used in protein purification-‐identification-‐function-‐expression studies, tissue culture and cell population analysis, cloning and genetic analysis. Define the immunological tests, microscopy techniques, tissue culture, flow cytometry, chromatography techniques and electrophoresis | PLO 9,15 | 1, 2, 3, 4, | A, B |
| Define subcellular organelles and their functions. | PLO 9,15 | 1, 2, 3, 4, | A, B |
| Define structure, organization and the functions of the membranes. | PLO 9,15 | 1, 2, 3, 4, | A, B |
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Define the structure and organization of the cytoskeleton
Explain the functions of the cytoskeleton Recognize the importance of adhesion in tissue structure Define adhesion-‐mediating molecules and their supportive role. |
PLO 9,15 | 1, 2, 3, 4, | A, B |
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Explain the mechanism of signal transduction
Explain the cell respond to changing environmental conditions
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PLO 9,15 | 1, 2, 3, 4, | A, B |
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Describe the molecules of intercellular communication
Explain how a cell receives, acts on, and alters its behavior in response to a signal from another cell |
PLO 9,15 | 1, 2, 3, 4, | A, B |
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Explain the programmed cell death
Describe the programmed cell death Explain the functions in the stages of life |
PLO 9,15 | 1, 2, 3, 4, | A, B |
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Define the phases of the cell cycle
Define the structure and organization of the molecules involved in the loop Define cell cycle associated diseases such as cancer. Describe the programmed cell death Explain the functions in the stages of life |
PLO 9,15 | 1, 2, 3, 4, | A, B |
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Apply both practical and theoretical knowledge necessary to laboratory skills.
Examine the phases of mitosis and meiosis division and defines the principles of genetics initiative. |
PLO 9,15 | 1, 2, 3, 4, | A, B |
| Identify and apply different methods of DNA isolation. | PLO 9,15 | 1, 2, 3, 4, | A, B |
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Distinguish physical measurements in accordance to their vector and scalar nature
Carry out mathematical operations on the measurements Explain the unit vector conception and its importance Make transformations between base and derived physical units List unit standards Define the Body-‐Mass Index |
PLO 9,15 | 1, 2, 3, 4, | A, B |
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Explain the Force conception and its effects
Explain the distinctions and resemblances between the conceptions of Force, Mass, Weight |
PLO 9,15 | 1, 2, 3, 4, | A, B |
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Explain Newton’s Gravitation Law and to formulate the importance of the law for the conceptions relationships listed in the 2nd item
Explain Newton’s 1st, 2nd and 3d Laws and the importance of them, and to debate the conditions of transforming the Laws to each other Explain the “Mass Center” concept and its importance |
PLO 9,15 | 1, 2, 3, 4, | A, B |
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Distinguish the differences between Energy and Work conceptions
Explain the condition of conversion of kinetic and potential energies into each other Explain the Energy Conservation and Conversion Principle Explain the Velocity, Acceleration and Moment conceptions, to tell the Moment Conservation Principle Explain the mechanical and biological importance of Force |
PLO 9,15 | 1, 2, 3, 4, | A, B |
| 1, 2, 3, 4, | A, B |
Course Flow
THEORETICAL COURSE CONTENT *FALL
| COURSE CONTENT (1.semester) | |||
| Week | Theoretical Topics | Study Materials | |
| 1 | Components and functions of the cell | Recommended resources | |
| 2 | Laboratory principles and DNA extraction | Recommended resources | |
| 3 | Fundamentals of biophysics | Recommended resources | |
| 4 | Bioelectronics and biooptics | Recommended resources | |
| 5 | Introduction to medical organic chemistry | Recommended resources | |
| 6 | Introduction to medical histology and embryology | Recommended resources | |
PRACTICAL COURSE CONTENT * FALL
| COURSE CONTENT (1.semester) | |||
| Week | Practical Topics | Study Materials | |
| 1 | Lab studies | Recommended resources | |
| 2 | Lab studies | Recommended resources | |
| 3 | Lab studies | Recommended resources | |
| 4 | Lab studies | Recommended resources | |
| 5 | Lab studies | Recommended resources | |
| 6 | Lab studies | Recommended resources | |
Recommended Sources
| Textbook |
1.Introductory Biophysics:Perspectives on the Living State. J.R.Claycomb and Jonathan Quoc P.Tran,,USA,2010
2.Biophysics, an Introduction Rodney M.J. Cotterill,England,2005 3.Biological Physics Philip C,Nelson,New York,2004 4.Organic Chemistry Mc Murry,Brooks-‐Cole ISBN-‐13:978-‐0-‐495-‐11258-‐7 5. Basic histology: text and atlas. Anthony Mescher, 12. edition, McGraw-‐Hill Medical (2009). 6. Histology and cell biology: an introduction to pathology Abraham L. Kierszenbaum A.L., Third Edition, Mosby (2011). 7. Oral Anatomy, Histology and Embryology. B.K.B. Berkovitz, G.R. Holland, B.J. Moxham, 4. editions, Mosby (2009). 8. Essentials of Oral Histology and Embryology: A Clinical Approach. James K. Avery, Daniel J. Chiego, 3. editions, Mosby (2005). |
| Additional Resources |
- Lecture notes
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Material Sharing
| Documents | Photocopy shareable. |
| Assignments | Shareable. |
| Exams | Not shareable. |
Assessment
| IN-TERM STUDIES | NUMBER | PERCENTAGE |
| Midterm Exam | 1 | 50 |
| Quiz | - | - |
| Homework | - | - |
| Total | 50 | |
| CONTRIBUTION OF FINAL EXAMINATION TO OVERALL GRADE | 50 | |
| CONTRIBUTION OF IN-TERM STUDIES TO OVERALL GRADE | 50 | |
| Total | 100 |
Course’s Contribution to Program
| No | Program Learning Outcomes | Contribution | |||||
| 1 | 2 | 3 | 4 | 5 | |||
| 9 | Integrating basic medical sciences in clinical sciences and using this information in all procedures of the patient. | X | |||||
| 15 | Following international literature, evaluating publications critically and integration of research results and evidence based dentistry during practice. | X | |||||
ECTS
| Activity | NUMBER |
Duration (Hours ) |
Total workload (Hours ) |
| Course duration 1st semester ( theoretical) | 6 | 10 | 60 |
| Course duration 1st semester ( practical ) | 6 | 1.5 | 9 |
| Studies outside the class ( 1st semester ) | 9 | 12 | 108 |
| TOTAL | 177 | ||
| Total workload /25 | 7.08 | ||
| ECTS credits of the course | 7 |